Evaluation of Wound Healing Parameters and Antibacterial Effect of Jojoba and Citrullus colocynthis Oils in Staphylococcus Wound Infection Induced in Mice

نویسندگان

چکیده

Staphylococcus aureus is responsible for most bacterial wound infections. Antibiotics are the first-line treatment; however, their indiscriminate use led to emergence of resistance. Alternative therapeutic options beyond antibiotic treatment required. Our study aimed evaluate and compare healing parameters antibacterial activity Jojoba Citrullus colocynthis oil extracts in In-vivo assessment inflammatory biomarkers, matrix metalloproteinase histopathological examination induced lesions were conducted mice. Levels interleukin 1 6 reduced, while metalloproteinases ratio; MMP-1 /MMP-9 was increased after topical application both essential oils. showed optimum compared other treated groups examination. In conclusion, preparation may be a promising alternative natural dermatological with enhanced activity.

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ژورنال

عنوان ژورنال: Journal of Pure and Applied Microbiology

سال: 2023

ISSN: ['2581-690X', '0973-7510']

DOI: https://doi.org/10.22207/jpam.17.2.01